Acetonitrile → [(3RS,4SR)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][N:11]([CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:12][CH:13]1[c:14]1[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]1)=[O:29].[CH3:39][C:40]#[N:41].[Cl:30][C:31]([O:32][CH2:33][C:34]([Cl:35])([Cl:36])[Cl:37])=[O:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][NH:11][CH2:12][CH:13]1[c:14]1[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]1)=[O:29]Participants
4
Sources & evidence
- ORD record
- ord-0b4cf08464b9437e896f898fb8ea7251
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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