Fluoride Ion → 1-(2-{4-[2-(4-Fluoro-phenyl)-6-methoxy-naphthalen-1-ylmethyl]-phenoxy}-ethyl)-piperidine

HRID 691648Notes

Reaction equation

HRID 691648 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([O:29][S:30]([C:31]([F:32])([F:33])[F:34])(=[O:35])=[O:36])[c:9]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)[c:10]2[cH:11][cH:12]1.[Cs+:48].[F-:47].[F:37][c:38]1[cH:39][cH:40][c:41]([B:44]([OH:45])[OH:46])[cH:42][cH:43]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](-[c:41]3[cH:40][cH:39][c:38]([F:37])[cH:43][cH:42]3)[c:9]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)[c:10]2[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 28179Fluoride IonHCID 104967Cesium cationHCID 2856454-Fluorophenylboronic acidHCID 57552542Trifluoromethanesulfonic acid 6-methoxy-1-[4-(2-piperidin-yl-ethoxy)-benzyl]-naphthalen-2-yl ester

Product 1

HCID 117517471-(2-{4-[2-(4-Fluoro-phenyl)-6-methoxy-naphthalen-1-ylmethyl]-phenoxy}-ethyl)-piperidine

Sources & evidence

ORD record
ord-2afcc61a3ba045e7ac78fc13fe132786
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…