Acetic Acid → N-cyclobutyl-8-fluoro-5-methoxy-N-propan-2-yl-3,4-dihydro-2H-chromen-3-amine
Reaction equation
[C:18]1(=[O:22])[CH2:19][CH2:20][CH2:21]1.[C:23]([BH3-:24])#[N:25].[CH3:27][C:28](=[O:29])[OH:30].[CH3:31][OH:32].[F:1][c:2]1[cH:3][cH:4][c:5]([O:16][CH3:17])[c:6]2[c:11]1[O:10][CH2:9][CH:8]([NH:12][CH:13]([CH3:14])[CH3:15])[CH2:7]2.[Na+:26]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:16][CH3:17])[c:6]2[c:11]1[O:10][CH2:9][CH:8]([N:12]([CH:13]([CH3:14])[CH3:15])[CH:18]1[CH2:19][CH2:20][CH2:21]1)[CH2:7]2Participants
7
Sources & evidence
- ORD record
- ord-c0eeefabe2c6420e87d473cc9b68bcc9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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