Acetone → 2-[4'-(2,3-Epoxypropoxy)phenyl]-3-(4'-methylbenzoyl)benzofuran

HRID 691961Notes

Reaction equation

HRID 691961 reaction equation
[Br:26][CH2:27][CH:28]1[CH2:29][O:30]1.[C:31](=[O:32])([O-:33])[O-:34].[CH3:37][C:38](=[O:39])[CH3:40].[K+:35].[K+:36].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([c:12]2[C:13]([c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)=[O:21])[cH:22][cH:23][cH:24][cH:25]3)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([c:12]2[C:13]([c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)=[O:21])[cH:22][cH:23][cH:24][cH:25]3)[cH:6][cH:7]1)[CH2:27][CH:28]1[CH2:29][O:30]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 18430EpibromohydrinHCID 19660Carbonate IonHCID 214879512-p-Hydroxyphenyl-3-p-methylbenzoylbenzofuran

Product 1

HCID 214880322-[4'-(2,3-Epoxypropoxy)phenyl]-3-(4'-methylbenzoyl)benzofuran

Sources & evidence

ORD record
ord-ca81c2cf1f594059a517790c6336022a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…