2-Bromo-5-methoxybenzoic acid → 2-(4-Chlorobenzoyl)-5-methoxybenzoic acid

HRID 692368Notes

Reaction equation

HRID 692368 reaction equation
[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([O:11][CH3:12])[cH:9][cH:10]1.[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[Cl:18][c:19]1[cH:20][cH:21][c:22]([C:23](=[O:24])[N:25]([O:26][CH3:27])[CH3:28])[cH:29][cH:30]1>>[c:2]1([C:23]([c:22]2[cH:21][cH:20][c:19]([Cl:18])[cH:30][cH:29]2)=[O:24])[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([O:11][CH3:12])[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 112756634-Chloro-N-methoxy-N-methylbenzamideHCID 178418339Butyllithium

Product 1

HCID 692132772-(4-Chlorobenzoyl)-5-methoxybenzoic acid

Sources & evidence

ORD record
ord-8a82045f22a14f3585e61f889cf0bd4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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