Toluene → N-(3-methylphenyl)-2-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Reaction equation
[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[CH:13]([NH:14][CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[cH:7][c:8]([CH3:12])[cH:9][cH:10][cH:11]1.[F:20][C:21]([c:22]1[c:23]([N:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[n:24][cH:25][cH:26][cH:27]1)([F:34])[F:35]>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[cH:7][c:8]([CH3:12])[cH:9][cH:10][cH:11]1)[N:31]1[CH2:30][CH2:29][N:28]([c:23]2[c:22]([C:21]([F:20])([F:34])[F:35])[cH:27][cH:26][cH:25][n:24]2)[CH2:33][CH2:32]1Participants
5
Sources & evidence
- ORD record
- ord-5ba8f8c5989d420e8ce777abf5d6c277
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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