HuagongsheHuagongshe Chemistry Print Report · For research reference only
{4-[3-(7-Fluoro-quinolin-6-ylmethyl)-imidazo[1,2-b]pyridazin-6-yl]-pyrazol-1-yl}-acetonitrile → HCID 57917311, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {4-[3-(7-Fluoro-quinolin-6-ylmethyl)-imidazo[1,2-b]pyridazin-6-yl]-pyrazol-1-yl}-acetonitrile | HCID 57917313 | — |
| Reactant | 5,7-Difluoro-6-[6-(1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-ylmethyl]-quinoline | HCID 136139430 | — |
| Product | HCID 57917311 | HCID 57917311 | — |
Reaction Steps
The title compound was prepared in analogy to the compound of Example 176 using 5,7-difluoro-6-[6-(1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-ylmethyl]-quinoline (Example 263) instead of 6-(6-chloro-imidazo[1,2-b]pyridazin-3-ylmethyl)-7-fluoro-quinoline (tR 3.28 min (conditions 13), MH+=402).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822468B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-ee2efbd9fab741498569387219e4e08e |
| Source note | uspto-grants-2014_09 |