4-Bromothiophene-2-carbonitrile → 4-[4-[2-[(2-Methylpyrrolidin-1-yl)methyl]pyrrolidine-1-carbonyl]phenyl]thiophene-2-carbonitrile
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:7]#[N:8])[s:5][cH:6]1.[CH3:9][CH:10]1[N:11]([CH2:15][CH:16]2[N:17]([C:21](=[O:22])[c:23]3[cH:24][cH:25][c:26]([B:29]4[O:30][C:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[O:37]4)[cH:27][cH:28]3)[CH2:18][CH2:19][CH2:20]2)[CH2:12][CH2:13][CH2:14]1>>[c:2]1(-[c:26]2[cH:25][cH:24][c:23]([C:21]([N:17]3[CH:16]([CH2:15][N:11]4[CH:10]([CH3:9])[CH2:14][CH2:13][CH2:12]4)[CH2:20][CH2:19][CH2:18]3)=[O:22])[cH:28][cH:27]2)[cH:3][c:4]([C:7]#[N:8])[s:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-42b86bfeaf51434e8b0d54d0080950a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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