Ethanol → Tert-butyl 7-oxo-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-8-carboxylate

HRID 692770Notes

Reaction equation

HRID 692770 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([CH:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[C:21](=[O:22])[O:23][CH3:24])[n:5][cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[CH3:27][CH2:28][OH:29].[H:25][H:26]>>[CH2:1]1[NH:2][C:21](=[O:22])[CH:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[c:4]2[c:3]1[cH:8][c:7]([C:9]([F:10])([F:11])[F:12])[cH:6][n:5]2

Participants

4

Reactant 3

HCID 702EthanolHCID 59017435tert-Butyl Methyl [3-Cyano-5-(trifluoromethyl)pyridin-2-yl]malonateHCID 178418361HCID 178418361, compound

Product 1

HCID 59017436Tert-butyl 7-oxo-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-8-carboxylate

Sources & evidence

ORD record
ord-fc7ce1009b7f48978f833af245ef0f57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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