1,4-Dioxane → 1-(2,2,2-Trifluoroethyl)piperidin-4-amine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15]([F:16])([F:17])[F:18])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:19].[O:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1>>[NH2:7][CH:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15]([F:16])([F:17])[F:18])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-501fd53ad6174eb0b894813c2ed1ac5b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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