1-(3-Bromophenyl)-4-methylpiperazine → [8-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

HRID 692945Notes

Reaction equation

HRID 692945 reaction equation
[Br:25][c:26]1[cH:27][c:28]([N:32]2[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]2)[cH:29][cH:30][cH:31]1.[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[c:12]3[n:13]([cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[n:21][c:22]([NH2:24])[n:23]3)[cH:9][cH:10]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[c:12]3[n:13]([cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[n:21][c:22]([NH:24][c:26]2[cH:27][c:28]([N:32]4[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]4)[cH:29][cH:30][cH:31]2)[n:23]3)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 534153291-(3-Bromophenyl)-4-methylpiperazineHCID 674814178-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 59612571[8-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

Sources & evidence

ORD record
ord-1f56ad15927e49c8b0c536d9cc673055
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…