Acetate → Ethyl 1-benzyloxycarbonylpiperidine-4-oxyacetate

HRID 693408Notes

Reaction equation

HRID 693408 reaction equation
[C:29]([O-:30])(=[O:31])[CH3:32].[C:33]([O-:34])(=[O:35])[CH3:36].[C:37]([O-:38])(=[O:39])[CH3:40].[C:41]([O-:42])(=[O:43])[CH3:44].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([OH:17])[CH2:15][CH2:16]1.[Cl:26][CH2:27][Cl:28].[N+:18](=[N-:19])=[CH:20][C:21](=[O:22])[O:23][CH2:24][CH3:25].[Rh+3:45].[Rh+3:46]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([O:17][CH2:20][C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 175Acetate4×HCID 6344DichloromethaneHCID 12192Ethyl diazoacetateHCID 167511Rhodium(3+)2×HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Product 1

HCID 23370004Ethyl 1-benzyloxycarbonylpiperidine-4-oxyacetate

Sources & evidence

ORD record
ord-a2b32582c57543cea9d94bf17b2929ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…