Dichloromethane → N-(3,4-Difluorobenzyl)-6-(4,5-dihydrooxazol-2-ylamino)-2-isopropyl-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamide

HRID 694017Notes

Reaction equation

HRID 694017 reaction equation
[Cl:33][CH2:34][CH2:35][N:36]=[C:37]=[O:38].[Cl:39][CH2:40][Cl:41].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:7]([CH:18]([CH3:19])[CH3:20])[n:8]([CH2:11][c:12]3[n:13][cH:14][cH:15][cH:16][cH:17]3)[c:9]2[cH:10]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:7]([CH:18]([CH3:19])[CH3:20])[n:8]([CH2:11][c:12]3[n:13][cH:14][cH:15][cH:16][cH:17]3)[c:9]2[cH:10]1)[C:37]1=[N:36][CH2:35][CH2:34][O:38]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 160352-Chloroethyl isocyanateHCID 59762386HCID 59762386, compound

Product 1

HCID 59762444N-(3,4-Difluorobenzyl)-6-(4,5-dihydrooxazol-2-ylamino)-2-isopropyl-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamide

Sources & evidence

ORD record
ord-e3011b8c01d04a858a3083da7e983d8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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