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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69418Generated: October 29, 2026

1-Acetylpiperazine → 2-{4-[3-(4-Acetylpiperazin-1-yl)pyrrolidin-1-yl]phenyl}-6-butoxy-3,4-dihydro-2H-isoquinolin-1-one

https://huagongshe.com/reaction/69418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AcetylpiperazineHCID 83795—
ReactantHCID 68988088HCID 68988088—
Product2-{4-[3-(4-Acetylpiperazin-1-yl)pyrrolidin-1-yl]phenyl}-6-butoxy-3,4-dihydro-2H-isoquinolin-1-oneHCID 57916704—

Reaction Steps

6-Butoxy-2-[4-(3-oxopyrrolidin-1-yl)phenyl]-3,4-dihydro-2H-isoquinolin-1-one was reacted with 1-piperazin-1-ylethanone by method J. The product with the molecular weight of 490.65 (C29H38N4O3) was obtained in this way; MS (ESI): 491 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-6a826a81dcd2417bb000a370cbee0968
Source noteuspto-grants-2014_09