反应详情

This was prepared in the same way as described in example 2/2 starting from 5-fluoroindole and butyraldehyde. The reaction, however, was heated under reflux for 24 hours. The end product was isolated and purified by chromatography on an SiO2 column using a hexane:ethyl ether gradient ranging from 7:3 to 4:6 as the eluent. Yield 45%.

1. customThis was prepared in the same way
2. customThe reaction
3. temperaturehowever, was heated
4. temperatureunder reflux for 24 hours
5. customThe end product was isolated
6. custompurified by chromatography on an SiO2 column