Dichloromethane → 3-Chloromethyl-2-cyclopropyl-6-(4-trifluoromethyl-phenyl)-pyridine

HRID 694265Notes

Reaction equation

HRID 694265 reaction equation
[CH:1]1([c:4]2[n:5][c:6](-[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]3)[cH:7][cH:8][c:9]2[CH2:10][OH:11])[CH2:2][CH2:3]1.[Cl:26][CH2:27][Cl:28].[S:22]([Cl:23])([Cl:24])=[O:25]>>[CH:1]1([c:4]2[n:5][c:6](-[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]3)[cH:7][cH:8][c:9]2[CH2:10][Cl:24])[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 21935842HCID 21935842, compound

Product 1

HCID 219359313-Chloromethyl-2-cyclopropyl-6-(4-trifluoromethyl-phenyl)-pyridine

Sources & evidence

ORD record
ord-a49eff13c73b4c3a9280554ad5d8fb64
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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