4-Butoxy-2-methylbenzoic acid → HCID 68989307, compound

HRID 69429Notes

Reaction equation

HRID 69429 reaction equation
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([OH:12])=O)=[C:8]([CH3:15])[CH:7]=1)[CH2:2][CH2:3][CH3:4].[N:16]1([C@@H:21]2[CH2:25][CH2:24][N:23]([C:26]3[CH:31]=[CH:30][C:29]([NH2:32])=[CH:28][C:27]=3[F:33])[CH2:22]2)[CH2:20][CH2:19][CH2:18][CH2:17]1>>[N:16]1([C@@H:21]2[CH2:25][CH2:24][N:23]([C:26]3[CH:31]=[CH:30][C:29]([NH:32][C:10](=[O:12])[C:9]4[CH:13]=[CH:14][C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])=[CH:7][C:8]=4[CH3:15])=[CH:28][C:27]=3[F:33])[CH2:22]2)[CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 534398994-Butoxy-2-methylbenzoic acidHCID 68988310HCID 68988310, compound

Product 1

HCID 68989307HCID 68989307, compound

Procedure

4-Butoxy-2-methyl-benzoic acid was reacted with (R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-fluorophenylamine according to Method P. In this way the product was obtained with molecular weight 439.58 (C26H34FN3O2); MS (ESI): 440 (M+H+).

Workup

  1. customIn this way the product was obtained with molecular weight 439.58 (C26H34FN3O2)

Sources & evidence

ORD record
ord-a5283f680f23480694759d8dadedda23
Source dataset
uspto-grants-2014_09
Patent number
US08822495B2

Reaction notes

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