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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 69437생성일: 2026년 10월 25일

2-(2-Chloroethyl)-4-methoxybenzoyl chloride → (S)-7-[4-(6-methoxy-1-oxo-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl]-2,7-diaza-spiro[4.4]nonane-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/69437

반응식

참여 물질

역할이름HCID투입량
반응물2-(2-Chloroethyl)-4-methoxybenzoyl chlorideHCID 12401186—
반응물(S)-7-(4-amino-phenyl)-2,7-diaza-spiro[4.4]nonane-2-carboxylic acid tert-butyl esterHCID 68994472—
생성물(S)-7-[4-(6-methoxy-1-oxo-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl]-2,7-diaza-spiro[4.4]nonane-2-carboxylic acid tert-butyl esterHCID 68990290—

반응 단계

According to Method A, 2-(2-chloroethyl)-4-methoxy-benzoyl chloride was reacted with (S)-7-(4-amino-phenyl)-2,7-diaza-spiro[4.4]nonane-2-carboxylic acid tert-butyl ester. In this way the product was obtained with molecular weight 477.61 (C28H35N3O4); MS (ESI): 478 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08822495B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-bdcf3269df004ea8a7f86e53f38608ea
출처 메모uspto-grants-2014_09