P-Anisidine → 6-chloro-N-(4-methoxyphenyl)nicotinamide

HRID 694419Notes

Reaction equation

HRID 694419 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH2:7])[cH:8][cH:9]1.[Cl:10][c:11]1[n:12][cH:13][c:14]([C:15](=[O:16])[Cl:17])[cH:18][cH:19]1.[Cl:20][c:21]1[cH:22][cH:23][c:24]([C:25]([NH:26][c:27]2[cH:28][cH:29][c:30]([I:31])[c:32]([CH3:33])[cH:34]2)=[O:35])[cH:36][n:37]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:7][C:15]([c:14]2[cH:13][n:12][c:11]([Cl:10])[cH:19][cH:18]2)=[O:16])[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 7732P-AnisidineHCID 27821656-Chloronicotinoyl ChlorideHCID 593181386-chloro-N-(4-iodo-3-methyl-phenyl)-nicotinamide

Product 1

HCID 14832696-chloro-N-(4-methoxyphenyl)nicotinamide

Sources & evidence

ORD record
ord-239a96d619e14277b414f1be7e3970ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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