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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69454Generated: October 25, 2026

2-Bromothiazole → HCID 57916905, compound

https://huagongshe.com/reaction/69454

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromothiazoleHCID 76430—
Reactant2-((R)-4-[1,3']Bipyrrolidinyl-1'-yl-3-fluoro-phenyl)-6-hydroxy-2H-isoquinolin-1-oneHCID 68989350—
ProductHCID 57916905HCID 57916905—

Reaction Steps

According to Method AB, 2-((R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-hydroxy-2H-isoquinolin-1-one was reacted with 2-bromothiazole. In this way the product was obtained with molecular weight 476.58 (C26H25FN4O2S); MS (ESI): 477 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-1da2ee3329fd469b873062f328b25fd7
Source noteuspto-grants-2014_09