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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69456Generated: October 25, 2026

4-Bromoaniline → 2-(4-bromophenyl)-6-butoxy-3,4-dihydro-2H-isoquinolin-1-one

https://huagongshe.com/reaction/69456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromoanilineHCID 7807—
Reactant4-Butoxy-2-(2-chloroethyl)benzoyl chlorideHCID 53440133—
Product2-(4-bromophenyl)-6-butoxy-3,4-dihydro-2H-isoquinolin-1-oneHCID 68991115—

Reaction Steps

According to Method A, 4-bromo-phenylamine was reacted with 4-butoxy-2-(2-chloroethyl)-benzoyl chloride. In this way the product was obtained with molecular weight 374.28 (C19H20BrNO2); MS (ESI): 374 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-0ce0a7a5fbc149c4a58b526ad48469b4
Source noteuspto-grants-2014_09