3-(1-Methanesulphonylpiperidin-4-yl)-3-phenylpropionaldehyde → 2-(1-{3-[1-(Methylsulfonyl)piperidin-4-yl]-3-phenylpropyl}piperidin-4-yl)-1,3-thiazole-4-carboxylic acid
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH:11]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([c:20]3[s:21][cH:22][c:23]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[n:24]3)[CH2:18][CH2:19]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[CH2:9][CH2:10]1.[CH3:36][S:37]([N:38]1[CH2:39][CH2:40][CH:41]([CH:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[CH2:49][CH:50]=[O:51])[CH2:52][CH2:53]1)(=[O:54])=[O:55].[NH:56]1[CH2:57][CH2:58][CH:59]([c:60]2[s:61][cH:62][c:63]([C:64]([O:65][CH2:66][CH3:67])=[O:68])[n:69]2)[CH2:70][CH2:71]1>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH:11]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([c:20]3[s:21][cH:22][c:23]([C:25](=[O:26])[OH:27])[n:24]3)[CH2:18][CH2:19]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[CH2:9][CH2:10]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d23f7653b08c4d38baef2bde8328c3e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…