HCID 68989917, compound → 4-(1,4-Dioxa-7-azaspiro[4.4]non-7-yl)-3-fluorophenylamine

HRID 69464Notes

Reaction equation

HRID 69464 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[N:11]1[CH2:19][CH2:18][C:13]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:12]1>[Pd]>[O:14]1[C:13]2([CH2:18][CH2:19][N:11]([C:3]3[CH:4]=[CH:5][C:6]([NH2:8])=[CH:7][C:2]=3[F:1])[CH2:12]2)[O:17][CH2:16][CH2:15]1

Participants

3

Reactant 1

HCID 68989917HCID 68989917, compound

Product 1

HCID 211054314-(1,4-Dioxa-7-azaspiro[4.4]non-7-yl)-3-fluorophenylamine

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

According to Method F, 7-(2-fluoro-4-nitro-phenyl)-1,4-dioxa-7-aza-spiro[4.4]nonane was reduced using Pd/C. In this way the product was obtained with molecular weight 238.26 (C12H15FN2O2); MS (ESI): 239 (M+H+).

Workup

  1. customIn this way the product was obtained with molecular weight 238.26 (C12H15FN2O2)

Sources & evidence

ORD record
ord-be336378809e4d9dba4f83d6ffd7dcff
Source dataset
uspto-grants-2014_09
Patent number
US08822495B2

Reaction notes

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