HRID69468

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COCC(C)N1CCCN(c2ccc(N3CCc4cc(O)ccc4C3=O)cc2OC)CC1

HCID68989135

未命名化合物

HCID68993549

未命名化合物

PRODUCTS

生成物

结构：COCC(C)N1CCCN(c2ccc(N3CCc4cc(OC[C@H]5CCCO5)ccc4C3=O)cc2OC)CC1

HCID57916837

未命名化合物

PROCEDURE

实验过程

6-Hydroxy-2-{3-methoxy-4-[4-(2-methoxy-1-methyl-ethyl)-[1,4]diazepan-1-yl]-phenyl}-3,4-dihydro-2H-isoquinolin-1-one and (R)-2-methanesulfonylmethyl-tetrahydrofuran were reacted according to Method K1. In this way the product was obtained with molecular weight 523.68 (C30H41N3O5); MS (ESI): 524 (M+H+).

WORKUP

后处理

customIn this way the product was obtained with molecular weight 523.68 (C30H41N3O5)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-66cab9aaff244343ad74e592e47d8a41
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08822495B2
来源说明: uspto-grants-2014_09

反应 SMILES

[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[N:7]([C:13]1[CH:18]=[CH:17][C:16]([N:19]3[CH2:25][CH2:24][CH2:23][N:22]([CH:26]([CH3:30])[CH2:27][O:28][CH3:29])[CH2:21][CH2:20]3)=[C:15]([O:31][CH3:32])[CH:14]=1)[CH2:6][CH2:5]2.CS([CH2:37][C@H:38]1[CH2:42][CH2:41][CH2:40][O:39]1)(=O)=O>>[CH3:32][O:31][C:15]1[CH:14]=[C:13]([N:7]2[CH2:6][CH2:5][C:4]3[C:9](=[CH:10][CH:11]=[C:2]([O:1][CH2:37][C@H:38]4[CH2:42][CH2:41][CH2:40][O:39]4)[CH:3]=3)[C:8]2=[O:12])[CH:18]=[CH:17][C:16]=1[N:19]1[CH2:25][CH2:24][CH2:23][N:22]([CH:26]([CH3:30])[CH2:27][O:28][CH3:29])[CH2:21][CH2:20]1