Acetic Acid → 1-[4-(3,4-dimethoxyphenyl)-7,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]ethanone

HRID 694756Notes

Reaction equation

HRID 694756 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([c:12]1[O:13][CH3:14])[CH2:10][NH:9][CH2:8][CH:7]2[c:15]1[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]1.[CH3:25][C:26]([OH:27])=[O:28].[Cl:29][CH2:30][Cl:31]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([c:12]1[O:13][CH3:14])[CH2:10][N:9]([C:26]([CH3:25])=[O:27])[CH2:8][CH:7]2[c:15]1[cH:16][c:17]([O:23][CH3:24])[c:18]([O:21][CH3:22])[cH:19][cH:20]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 6344DichloromethaneHCID 147195577,8-Dimethoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 199596961-[4-(3,4-dimethoxyphenyl)-7,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]ethanone

Sources & evidence

ORD record
ord-42e95ae61da441c986a0b7e87598ea11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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