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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 694840Generated: October 29, 2026

Tetrahydrofuran → 2-[(2-Chloro-6-fluorophenyl)amino]-7,7-dimethyl-N-[2-methyl-4-(trifluoromethyl)phenyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide

https://huagongshe.com/reaction/694840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantThionyl ChlorideHCID 24386—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-Amino-3-methylbenzotrifluorideHCID 13750437—
ReactantHCID 178422815HCID 178422815—
Product2-[(2-Chloro-6-fluorophenyl)amino]-7,7-dimethyl-N-[2-methyl-4-(trifluoromethyl)phenyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamideHCID 178426040—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-249561ce52324cd4bc8289c5c805f986
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)