Methanol → 2-Amino-5-(4-difluoromethoxy-phenyl)-5-[3-(isopropylamino-methyl)-phenyl]-3-methyl-3,5-dihydro-imidazol-4-one
Reaction equation
[BH4-:31].[CH3:27][CH:28]([CH3:29])[NH2:30].[CH3:35][OH:36].[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH:20]=[O:21])[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26].[Na+:32].[Na+:34].[OH-:33]>>[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH2:20][NH:30][CH:28]([CH3:27])[CH3:29])[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26]Participants
7
Sources & evidence
- ORD record
- ord-f95a3843ab7c48dcb6bd95a75b4c3f84
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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