HCID 68990224, compound → HCID 68988046, compound

HRID 69485Notes

Reaction equation

HRID 69485 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[N:11]1[CH2:15][CH2:14][C@@H:13]([NH:16][CH2:17][C:18]([CH3:21])([OH:20])[CH3:19])[CH2:12]1>[Pd]>[NH2:8][C:6]1[CH:5]=[CH:4][C:3]([N:11]2[CH2:15][CH2:14][C@@H:13]([NH:16][CH2:17][C:18]([CH3:19])([OH:20])[CH3:21])[CH2:12]2)=[C:2]([F:1])[CH:7]=1

Participants

3

Reactant 1

HCID 68990224HCID 68990224, compound

Product 1

HCID 68988046HCID 68988046, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

1-[(R)-1-(2-Fluoro-4-nitro-phenyl)-pyrrolidin-3-ylamino]-2-methyl-propan-2-ol was reduced according to Method F using Pd/C. In this way the product was obtained with molecular weight 267.17 (C14H22FN30); MS (ESI): 268 (M+H+).

Workup

  1. customIn this way the product was obtained with molecular weight 267.17 (C14H22FN30)

Sources & evidence

ORD record
ord-6d0bd70f97284eebbe0dd41e3d107b84
Source dataset
uspto-grants-2014_09
Patent number
US08822495B2

Reaction notes

Loading…