Propargyl bromide → 3-Chloro-2-(4-chloro-2-fluoro-5-propargyloxyphenyl)-5-trifluoromethylpyridine

HRID 695073Notes

Reaction equation

HRID 695073 reaction equation
[CH2:43]([Br:44])[C:45]#[CH:46].[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([O:19][CH2:20][C:21]#[CH:22])[c:15]([Cl:18])[cH:16][cH:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Cl:23][c:24]1[c:25](-[c:26]2[cH:27][c:28]([OH:29])[c:30]([Cl:32])[cH:33][c:34]2[F:35])[n:36][cH:37][c:38]([C:39]([F:31])([F:40])[F:41])[cH:42]1>>[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([O:19][CH2:20][C:21]#[CH:22])[c:15]([Cl:18])[cH:16][c:17]2[F:31])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

4

Reactant 3

HCID 7842Propargyl bromideHCID 118235682-Chloro-5-(3-chloro-5-trifluoromethylpyrid-2-yl)-4-fluorophenolHCID 190687583-Chloro-2-(4-chloro-3-propargyloxyphenyl)-5-trifluoromethylpyridine

Product 1

HCID 114513523-Chloro-2-(4-chloro-2-fluoro-5-propargyloxyphenyl)-5-trifluoromethylpyridine

Sources & evidence

ORD record
ord-e22cc6ed94df46a380a3bbf3c6106325
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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