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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69510Generated: October 30, 2026

(S)-1-(tetrahydrofuran-2-yl)methyl methanesulfonate → 6-[(S)-1-(Tetrahydrofuran-2-yl)methoxy]isochroman-1-one

https://huagongshe.com/reaction/69510

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-1-(tetrahydrofuran-2-yl)methyl methanesulfonateHCID 18649743—
Reactant6-Hydroxyisochroman-1-oneHCID 55275183—
Product6-[(S)-1-(Tetrahydrofuran-2-yl)methoxy]isochroman-1-oneHCID 66679924—

Reaction Steps

6-Hydroxy-isochroman-1-one was reacted with Methanesulfonic acid (S)-1-(tetrahydro-furan-2-yl)methyl ester by method K1. The product with the molecular weight of 248.28 (C14H28FN3O3) was obtained in this way; MS (ESI): 249 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-9f1b5cd813824eb0918c0a20c665674d
Source noteuspto-grants-2014_09