Pyridine → N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

HRID 695362Notes

Reaction equation

HRID 695362 reaction equation
[Cl:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[NH:10][C:9](=[O:14])[CH2:8]2.[Cl:30][CH2:31][Cl:32].[F:15][c:16]1[cH:17][cH:18][c:19]([CH2:20][NH2:21])[cH:22][cH:23]1.[cH:24]1[cH:25][cH:26][n:27][cH:28][cH:29]1>>[S:2](=[O:3])(=[O:4])([c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[NH:10][C:9](=[O:14])[CH2:8]2)[NH:21][CH2:20][c:19]1[cH:18][cH:17][c:16]([F:15])[cH:23][cH:22]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 673264-FluorobenzylamineHCID 49625062-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride

Product 1

HCID 9266705N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

Sources & evidence

ORD record
ord-275f5685fa7549efa8a846f96df6d7a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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