3-(5-Bromo-thiazol-2-yl)-1-cyclohexyl-1-(tetrahydro-pyran-4-yl)-urea → 2-{2-[3-Cyclohexyl-3-(tetrahydro-pyran-4-yl)-ureido]-thiazol-5-ylsulfanyl}-1H-imidazole-4-carboxylic acid ethyl ester
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([NH:7][C:8]([N:9]([CH:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)=[O:22])[s:6]1.[CH2:23]([CH3:24])[O:25][C:26](=[O:27])[c:28]1[n:29][c:30]([SH:33])[nH:31][cH:32]1>>[c:2]1([S:33][c:30]2[n:29][c:28]([C:26]([O:25][CH2:23][CH3:24])=[O:27])[cH:32][nH:31]2)[cH:3][n:4][c:5]([NH:7][C:8]([N:9]([CH:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)=[O:22])[s:6]1Participants
3
Sources & evidence
- ORD record
- ord-a72983277aaf4dbabe032406e78794e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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