Methanol → 5-(3-Methyl-3,8-diazabicyclo[3.2.1]octan-8-yl)pyridin-2-amine

HRID 695627Notes

Reaction equation

HRID 695627 reaction equation
[CH3:25][N:26]1[CH2:27][CH:28]2[CH2:29][CH2:30][CH:31]([CH2:32]1)[N:33]2[c:34]1[cH:35][n:36][c:37]([N+:40]([O-:41])=[O:42])[cH:38][cH:39]1.[CH3:43][OH:44].[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[cH:7][cH:8][c:9]([N:10]3[CH2:11][CH2:12][C:13]([OH:14])([CH3:15])[CH2:16][CH2:17]3)[cH:18][n:19]2)[c:20](=[O:21])[n:22]([CH3:23])[n:24]1>>[CH3:25][N:26]1[CH2:27][CH:28]2[CH2:29][CH2:30][CH:31]([CH2:32]1)[N:33]2[c:34]1[cH:35][n:36][c:37]([NH2:40])[cH:38][cH:39]1

Participants

4

Reactant 3

HCID 887MethanolHCID 667429326-chloro-4-(5-(4-hydroxy-4-methylpiperidin-1-yl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-oneHCID 680624973-Methyl-8-(6-nitro-3-pyridinyl)-3,8-diazabicyclo[3.2.1]octane

Product 1

HCID 667431655-(3-Methyl-3,8-diazabicyclo[3.2.1]octan-8-yl)pyridin-2-amine

Sources & evidence

ORD record
ord-4d60a24a96754ac0b463a8d5635a6eac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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