Dichloromethane → 4-(2,2-dimethylpropyl)-2-[1-fluoro-2-(4-pyridin-2-ylphenyl)ethyl]-N,N-dimethyl-1H-imidazole-1-sulfonamide
Reaction equation
[CH2:1]([N:2]([S:3]([F:4])([F:5])[F:7])[CH2:6][CH3:8])[CH3:9].[CH2:41]([Cl:42])[Cl:43].[CH3:10][C:11]([CH2:12][c:13]1[n:14][c:15]([CH:24]([CH2:25][c:26]2[cH:27][cH:28][c:29](-[c:32]3[n:33][cH:34][cH:35][cH:36][cH:37]3)[cH:30][cH:31]2)[OH:38])[n:16]([S:18](=[O:19])(=[O:20])[N:21]([CH3:22])[CH3:23])[cH:17]1)([CH3:39])[CH3:40]>>[F:7][CH:24]([c:15]1[n:14][c:13]([CH2:12][C:11]([CH3:10])([CH3:39])[CH3:40])[cH:17][n:16]1[S:18](=[O:19])(=[O:20])[N:21]([CH3:22])[CH3:23])[CH2:25][c:26]1[cH:27][cH:28][c:29](-[c:32]2[n:33][cH:34][cH:35][cH:36][cH:37]2)[cH:30][cH:31]1Participants
4
Sources & evidence
- ORD record
- ord-d2b82de4bd39476ba52d4d1ff79c13c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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