Pentanamide, 2-amino-4-methyl- → N-(1-amino-4-methyl-1-oxopentan-2-yl)-6-(cyclopropylmethoxy)-5-(oxolan-2-yl)pyridine-2-carboxamide

HRID 695825Notes

Reaction equation

HRID 695825 reaction equation
[C:39]([NH2:40])(=[O:41])[CH:42]([CH2:43][CH:44]([CH3:45])[CH3:46])[NH:47][C:48]([c:49]1[cH:50][cH:51][c:52]([CH:53]2[CH2:54][CH2:55][O:56][CH2:57]2)[c:58]([O:59][CH2:60][CH:61]2[CH2:62][CH2:63]2)[n:64]1)=[O:65].[CH:1]1([CH2:2][O:3][c:4]2[n:5][c:6]([C:7]([OH:8])=[O:9])[cH:10][cH:11][c:12]2[CH:13]2[CH2:14][CH2:15][O:16][CH2:17]2)[CH2:18][CH2:19]1.[CH:20]1([CH2:23][O:24][c:25]2[c:26]([CH:34]3[O:35][CH2:36][CH2:37][CH2:38]3)[cH:27][cH:28][c:29]([C:31](=[O:32])[OH:33])[n:30]2)[CH2:21][CH2:22]1.[NH2:66][CH:67]([CH2:68][CH:69]([CH3:70])[CH3:71])[C:72]([NH2:73])=[O:74]>>[CH:20]1([CH2:23][O:24][c:25]2[c:26]([CH:34]3[O:35][CH2:36][CH2:37][CH2:38]3)[cH:27][cH:28][c:29]([C:31](=[O:33])[NH:47][CH:42]([C:39]([NH2:40])=[O:41])[CH2:43][CH:44]([CH3:45])[CH3:46])[n:30]2)[CH2:21][CH2:22]1

Participants

5

Reactant 4

HCID 114616Pentanamide, 2-amino-4-methyl-HCID 710873686-(Cyclopropylmethoxy)-5-(tetrahydrofuran-2-yl)-pyridine-2-carboxylic acidHCID 710873756-(Cyclopropylmethoxy)-5-(tetrahydrofuran-3-yl)-pyridine-2-carboxylic acidHCID 78010113N-(1-amino-4-methyl-1-oxopentan-2-yl)-6-(cyclopropylmethoxy)-5-(oxolan-3-yl)pyridine-2-carboxamide

Product 1

HCID 78010114N-(1-amino-4-methyl-1-oxopentan-2-yl)-6-(cyclopropylmethoxy)-5-(oxolan-2-yl)pyridine-2-carboxamide

Sources & evidence

ORD record
ord-c793ed3d852a4009984a3741e8a69b84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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