3-Fluoro-5-hydroxybenzeneboronic acid → 1-(1,3-Dimethyl-1H-pyrazol-4-yl)-8-(3-fluoro-5-hydroxy-phenyl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

HRID 695996Notes

Reaction equation

HRID 695996 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([CH3:21])[n:17][n:18]([CH3:20])[cH:19]1.[F:24][c:25]1[cH:26][c:27]([B:32]([OH:33])[OH:34])[cH:28][c:29]([OH:31])[cH:30]1>>[c:2]1(-[c:27]2[cH:26][c:25]([F:24])[cH:30][c:29]([OH:31])[cH:28]2)[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([CH3:21])[n:17][n:18]([CH3:20])[cH:19]1

Participants

3

Reactant 2

HCID 447173083-Fluoro-5-hydroxybenzeneboronic acidHCID 596197398-Bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

Product 1

HCID 596199941-(1,3-Dimethyl-1H-pyrazol-4-yl)-8-(3-fluoro-5-hydroxy-phenyl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

Sources & evidence

ORD record
ord-ec24c0762b6c4ea0bccbadc992495c87
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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