2-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methyl-pyrimidine → N-tert-Butyl-5-{3-[6-(4-chloro-phenyl)-4-methyl-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

HRID 696520Notes

Reaction equation

HRID 696520 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:21])[cH:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1.[C:22]([CH3:23])([CH3:24])([CH3:25])[NH:26][S:27](=[O:28])(=[O:29])[c:30]1[s:31][c:32]([B:35]2[O:36][C:37]([CH3:38])([CH3:39])[C:40]([CH3:41])([CH3:42])[O:43]2)[cH:33][cH:34]1>>[c:2]1(-[c:32]2[s:31][c:30]([S:27]([NH:26][C:22]([CH3:23])([CH3:24])[CH3:25])(=[O:28])=[O:29])[cH:34][cH:33]2)[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:21])[cH:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 574687612-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methyl-pyrimidineHCID 57468817N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide

Product 1

HCID 57468910N-tert-Butyl-5-{3-[6-(4-chloro-phenyl)-4-methyl-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-2138bab4c51a4841929c2fc2cc6562e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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