ethyl (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetate → (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetic acid

HRID 696541Notes

Reaction equation

HRID 696541 reaction equation
[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:25][C:26](=[O:27])[O:28][CH2:29][CH3:30])[C:9](=[O:24])[C:10]21[c:11]2[c:12]([cH:15][c:16]3[c:20]([cH:21]2)[CH2:19][C:18]([CH3:22])([CH3:23])[O:17]3)[O:13][CH2:14]1.[O:31]=[C:32]1[C:33]2([c:34]3[cH:35][c:36]4[c:40]([cH:41][c:42]3[O:43][CH2:44]2)[O:39][CH2:38][O:37]4)[c:45]2[c:46]([cH:47][cH:48][cH:49][cH:50]2)[N:51]1[CH2:52][C:53]([O:54][CH2:55][CH3:56])=[O:57]>>[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:25][C:26](=[O:27])[OH:28])[C:9](=[O:24])[C:10]21[c:11]2[c:12]([cH:15][c:16]3[c:20]([cH:21]2)[CH2:19][C:18]([CH3:22])([CH3:23])[O:17]3)[O:13][CH2:14]1

Participants

3

Reactant 2

HCID 59263323ethyl (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetateHCID 59263415ethyl(2'-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-1'(2'H)-yl)acetate

Product 1

HCID 66642718(4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetic acid

Sources & evidence

ORD record
ord-c4ce99b4af8a47d983b1d439d127772b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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