Dichloromethane → 8-Pyrimidin-2-yl-1,4-dioxa-spiro[4.5]decan-8-ol
Reaction equation
[Br:1][c:2]1[n:3][cH:4][cH:5][cH:6][n:7]1.[CH2:24]([Cl:25])[Cl:26].[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32].[O:13]1[CH2:14][CH2:15][O:16][C:17]12[CH2:18][CH2:19][C:20](=[O:23])[CH2:21][CH2:22]2>>[c:2]1([C:20]2([OH:23])[CH2:19][CH2:18][C:17]3([O:13][CH2:14][CH2:15][O:16]3)[CH2:22][CH2:21]2)[n:3][cH:4][cH:5][cH:6][n:7]1Participants
6
Sources & evidence
- ORD record
- ord-5356db4258094046857523fdfea5e382
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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