Hydroxide → Tert-butyl 2-[[1-cyano-2-(4-iodophenyl)ethyl]carbamoyl]piperidine-1-carboxylate

HRID 696724Notes

Reaction equation

HRID 696724 reaction equation
[CH3:30][O:31][C:32]([NH:33][S:34]([N+:35]([CH2:36][CH3:37])([CH2:38][CH3:39])[CH2:40][CH3:41])(=[O:42])=[O:43])=[O:44].[Cl:45][CH2:46][Cl:47].[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[CH:15]1[N:16]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:17][CH2:18][CH2:19][CH2:20]1)=[O:28].[OH-:29]>>[N:1]#[C:2][CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[CH:15]1[N:16]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:17][CH2:18][CH2:19][CH2:20]1

Participants

5

Reactant 4

HCID 961HydroxideHCID 6344DichloromethaneHCID 2724995Triethyl(methoxycarbonylsulfamoyl)aminiumHCID 76700698Tert-butyl 2-[[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamoyl]piperidine-1-carboxylate

Product 1

HCID 76700690Tert-butyl 2-[[1-cyano-2-(4-iodophenyl)ethyl]carbamoyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-724345d151164ec19d206194402f69ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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