Potassium Cation → Tert-butyl 4-(4-allyloxyphenyl)-3-hydroxypiperidine-1-carboxylate

HRID 696869Notes

Reaction equation

HRID 696869 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH2:22]([CH:23]=[CH2:24])[Br:25].[K+:30].[K+:31].[OH:1][CH:2]1[CH2:3][N:4]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([OH:14])[cH:12][cH:13]1>>[OH:1][CH:2]1[CH2:3][N:4]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:24][CH:23]=[CH2:22])[cH:12][cH:13]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 7841Allyl bromideHCID 19660Carbonate IonHCID 21713087(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate

Product 1

HCID 54331732Tert-butyl 4-(4-allyloxyphenyl)-3-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-e209fc662d644d2b858175116742d789
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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