Water → 4-Chloro-3-(4-chloro-2-fluoro-5-hydroxyphenyl)-1-methyl-5-trifluoromethyl-1H-pyrazole

HRID 696974Notes

Reaction equation

[B:22]([Br:23])([Br:24])[Br:25].[CH2:27]([Cl:28])[Cl:29].[Cl:1][c:2]1[c:3](-[c:12]2[c:13]([F:21])[cH:14][c:15]([Cl:20])[c:16]([O:18][CH3:19])[cH:17]2)[n:4][n:5]([CH3:11])[c:6]1[C:7]([F:8])([F:9])[F:10].[OH2:26]>>[Cl:1][c:2]1[c:3](-[c:12]2[c:13]([F:21])[cH:14][c:15]([Cl:20])[c:16]([OH:18])[cH:17]2)[n:4][n:5]([CH3:11])[c:6]1[C:7]([F:8])([F:9])[F:10]

Participants

Reactant 4

HCID 962Water

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 186156481-Methyl-3-(2-fluoro-4-chloro-5-methoxyphenyl)-4-chloro-5-trifluoromethyl-1H-pyrazole

Product 1

HCID 111210244-Chloro-3-(4-chloro-2-fluoro-5-hydroxyphenyl)-1-methyl-5-trifluoromethyl-1H-pyrazole

Sources & evidence

ORD record: ord-482f9c87ed6b437b8a2abb44f0ef0283
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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