Fluoride Ion → N-(3,5-Bis-trifluoromethyl-benzyl)-N-(9-methyl-7-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl)-acetamide
Reaction equation
[CH3:36][B:37]([OH:38])[OH:39].[Cs+:41].[F-:40].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([C:8]([CH3:9])=[O:10])[CH:11]2[c:12]3[c:13]([c:18]([Br:26])[cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]3)[NH:14][CH2:15][CH2:16][CH2:17]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([C:8]([CH3:9])=[O:10])[CH:11]2[c:12]3[c:13]([c:18]([CH3:36])[cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]3)[NH:14][CH2:15][CH2:16][CH2:17]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-de0c74ef8e914f87bc414518c9a3c7d9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…