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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 697156Generated: October 29, 2026

1,2-Dichloroethane → 3-(4-Hydroxy-2-{[(pyrazine-2-carbonyl)-amino]-methyl}-phenyl)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/697156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantWaterHCID 962—
Reactant2-Pyrazinecarboxylic acidHCID 1047—
ReactantDichloromethaneHCID 6344—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantTert-butyl-3-[2-(aminomethyl)-4-hydroxyphenyl]propanoateHCID 17984622—
Product3-(4-Hydroxy-2-{[(pyrazine-2-carbonyl)-amino]-methyl}-phenyl)-propionic acid tert-butyl esterHCID 58979014—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-a056381a2f654b1aa197b9c2200dd657
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)