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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 697243Generated: October 28, 2026

Dichloromethane → 3-chloro-N-[(4,4-difluoropyrrolidin-2-yl)methyl]aniline

https://huagongshe.com/reaction/697243

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert-butyl 2-[(3-chloroanilino)methyl]-4,4-difluoropyrrolidine-1-carboxylateHCID 66774597—
Product3-chloro-N-[(4,4-difluoropyrrolidin-2-yl)methyl]anilineHCID 66773666—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-fef74ce19c6a4b5c90591c5a1ff7e9ba
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)