3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester → {2-Dimethylamino-2'-fluoro-5-(3-oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]([N:22]([CH3:23])[CH3:24])[c:11](-[c:15]2[c:16]([F:21])[cH:17][cH:18][cH:19][cH:20]2)[cH:12][c:13]1[NH2:14])=[O:25].[C:26]([CH3:28])([CH3:29])([O:30][C:31](=[O:27])[CH2:32][C:33]([c:34]1[cH:35][c:36](-[c:40]2[cH:41][cH:42][n:43][cH:44][cH:45]2)[cH:37][cH:38][cH:39]1)=[O:46])[CH3:47]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]([N:22]([CH3:23])[CH3:24])[c:11](-[c:15]2[c:16]([F:21])[cH:17][cH:18][cH:19][cH:20]2)[cH:12][c:13]1[NH:14][C:31](=[O:30])[CH2:32][C:33]([c:34]1[cH:35][c:36](-[c:40]2[cH:41][cH:42][n:43][cH:44][cH:45]2)[cH:37][cH:38][cH:39]1)=[O:46])=[O:25]Participants
3
Sources & evidence
- ORD record
- ord-17cab7ef1c284aefa95d7115ba2f6658
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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