1-(2,5-Difluoro-4-methoxyphenyl)-4-(3-phenylpropyl)piperidine → 2,5-Difluoro-4-[4-(3-phenylpropyl)piperidino]phenol
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([N:7]2[CH2:8][CH2:9][N:10]([CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:19][CH2:20]2)[cH:21][c:22]1[CH3:23].[F:24][c:25]1[c:26]([N:34]2[CH2:35][CH2:36][CH:37]([CH2:40][CH2:41][CH2:42][c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[CH2:38][CH2:39]2)[cH:27][c:28]([F:33])[c:29]([O:31][CH3:32])[cH:30]1>>[F:24][c:25]1[c:26]([N:34]2[CH2:35][CH2:36][CH:37]([CH2:40][CH2:41][CH2:42][c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[CH2:38][CH2:39]2)[cH:27][c:28]([F:33])[c:29]([OH:31])[cH:30]1Participants
3
Sources & evidence
- ORD record
- ord-d8d6c4e9775442c8822c5f0877588d2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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