Methanol → 5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridine

HRID 697639Notes

Reaction equation

HRID 697639 reaction equation
[C:53](#[N:54])[CH3:55].[CH3:47][OH:48].[Cl:49][CH2:50][Cl:51].[OH2:52].[cH:1]1[c:2]2[c:22]([cH:23][cH:24][cH:46]1)-[c:17]1[c:16]([cH:21][cH:20][cH:19][cH:18]1)[CH:3]2[CH2:4][O:5][C:6](=[O:7])[NH:8][CH:9]([C:10](=[O:11])[n:25]1[cH:26][c:27]([CH:35]([CH3:36])[c:37]2[c:38]([Cl:45])[c:39]([F:44])[cH:40][cH:41][c:42]2[Cl:43])[c:28]2[c:29]1[n:30][cH:31][c:32]([Br:34])[cH:33]2)[CH2:12][CH:13]([CH3:14])[CH3:15]>>[nH:25]1[cH:26][c:27]([CH:35]([CH3:36])[c:37]2[c:38]([Cl:45])[c:39]([F:44])[cH:40][cH:41][c:42]2[Cl:43])[c:28]2[c:29]1[n:30][cH:31][c:32]([Br:34])[cH:33]2

Participants

6

Reactant 5

HCID 887MethanolHCID 962WaterHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 767841859H-fluoren-9-ylmethyl N-[1-[5-bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethyl]pyrrolo[2,3-b]pyridin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamate

Product 1

HCID 584314405-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-4110b8447f504067b4d003f5ea005194
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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