Chloroform → 2-[4-(Chloromethyl)phenyl]-4-(pyrrolidin-1-ylcarbonyl)-1,3-oxazole
Reaction equation
[Cl:34][CH2:35][Cl:36].[Cl:37][CH:38]([Cl:39])[Cl:40].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[o:10][cH:11][c:12]([C:14](=[O:15])[N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1.[S:21]([Cl:22])([Cl:23])=[O:24].[nH:25]1[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[o:10][cH:11][c:12]([C:14](=[O:15])[N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1)[Cl:23]Participants
6
Sources & evidence
- ORD record
- ord-99b12019176f4556b663677fc3c78e16
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…