Ethanol → 5-Chloro-2-(2-isopropyl-1H-imidazol-1-yl)aniline

HRID 698057Notes

Reaction equation

HRID 698057 reaction equation
[CH3:24][CH2:25][OH:26].[CH:29]([Cl:30])([Cl:31])[Cl:32].[Cl:1][c:2]1[cH:3][c:4]([N+:16]([O-:17])=[O:18])[c:5](-[n:8]2[c:9]([CH:13]([CH3:14])[CH3:15])[n:10][cH:11][cH:12]2)[cH:6][cH:7]1.[Na+:28].[OH-:27].[OH2:19].[OH2:20].[Sn:21]([Cl:22])[Cl:23]>>[Cl:1][c:2]1[cH:3][c:4]([NH2:16])[c:5](-[n:8]2[c:9]([CH:13]([CH3:14])[CH3:15])[n:10][cH:11][cH:12]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962Water2×HCID 6212ChloroformHCID 24479Stannous ChlorideHCID 591988521-(4-Chloro-2-nitrophenyl)-2-isopropyl-1H-imidazole

Product 1

HCID 285030025-Chloro-2-(2-isopropyl-1H-imidazol-1-yl)aniline

Sources & evidence

ORD record
ord-0785cb8183264280be2bc7a5a5386924
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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